Rabbit Secondary Antibodies
ABclonal Technology 594 Rabbit anti-Human DLL4
This gene is a homolog of the Drosophila delta gene The delta gene family encodes Notch ligands that are characterized by a DSL domain EGF repeats and a transmembrane domain
ABclonal Technology 488 Rabbit anti-Human DLL4
This gene is a homolog of the Drosophila delta gene The delta gene family encodes Notch ligands that are characterized by a DSL domain EGF repeats and a transmembrane domain
ABclonal Technology 594 Rabbit anti-Human CD72
Predicted to enable signaling receptor binding activity Predicted to be involved in cell adhesion Is integral component of plasma membrane
Cayman Chemical Grnzyme BCTerm RabbIt Mo 100uL
An androgenically inactive metabolite of testosterone and androstenedione potentiates GABA-induced chloride currents in HEK293 cells expressing rat a1B2Y2L subunit-containing GABAA receptors at 10 UM protective against seizures induced by 6 Hz electroshock or PTZ (ED50s 76 9 and 139 mg/kg respectively) increases body temperature in rhesus macaques
ABclonal Technology APC Rabbit anti-Mouse IL-13
Predicted to enable interleukin-13 receptor binding activity Involved in positive regulation of cold-induced thermogenesis and positive regulation of macrophage activation Acts upstream of or within cellular response to cytokine stimulus inflammatory response and positive regulation of immune effector process Located in cytoplasm external side of plasma membrane and extracellular space Is expressed in gut liver male reproductive gland or organ and thymus Used to study atopic dermatitis Human ortholog(s) of this gene implicated in several diseases including allergic disease (multiple) autoimmune disease (multiple) diffuse scleroderma lung disease (multiple) and nose disease (multiple) Orthologous to human IL13 (interleukin 13)
Abcam Rabbit Anti-Mouse IgG H&L (Biotin)
Rabbit Anti-Mouse IgG H&L (Biotin)
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology NFYA Rabbit mAb
The protein encoded by this gene is one subunit of a trimeric complex forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes Subunit A associates with a tight dimer composed of the B and C subunits resulting in a trimer that binds to DNA with high specificity and affinity The sequence specific interactions of the complex are made by the A subunit suggesting a role as the regulatory subunit In addition there is evidence of post-transcriptional regulation in this gene product either by protein degradation or control of translation Further regulation is represented by alternative splicing in the glutamine-rich activation domain with clear tissue-specific preferences for the two isoforms
ABclonal Technology FGF23 Rabbit mAb
This gene encodes a member of the fibroblast growth factor family of proteins which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes The product of this gene regulates phosphate homeostasis and transport in the kidney The full-length functional protein may be deactivated via cleavage into N-terminal and C-terminal chains Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR) Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC)
Abcam Rabbit Anti-Mouse IgG H&L Alexa Fluor 568 preadsorbed
Rabbit Anti-Mouse IgG H&L Alexa Fluor 568 preadsorbed
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology CCL17 Rabbit mAb
This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16 Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes The CC cytokines are proteins characterized by two adjacent cysteines The cytokine encoded by this gene displays chemotactic activity for T lymphocytes but not monocytes or granulocytes The product of this gene binds to chemokine receptors CCR4 and CCR8 This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells
ABclonal Technology H2-Ab1 Rabbit mAb
Enables several functions including peptide antigen binding activity protein antigen binding activity and toxic substance binding activity Involved in several processes including B cell affinity maturation cellular response to interferon-gamma and positive regulation of T-helper 1 type immune response Acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II and immune response Located in Golgi apparatus endosome and external side of plasma membrane Is integral component of membrane Part of MHC class II protein complex Is expressed in lung metanephros and thymus primordium Orthologous to human HLA-DQB2 (major histocompatibility complex class II DQ beta 2)
ABclonal Technology TrkB Rabbit mAb
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family This kinase is a membrane-bound receptor that upon neurotrophin binding phosphorylates itself and members of the MAPK pathway Signalling through this kinase leads to cell differentiation Mutations in this gene have been associated with obesity and mood disorders Alternative splicing results in multiple transcript variants
ABclonal Technology Calretinin Rabbit mAb
This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily Members of this protein family have six EF-hand domains which bind calcium This protein plays a role in diverse cellular functions including message targeting and intracellular calcium buffering It also functions as a modulator of neuronal excitability and is a diagnostic marker for some human diseases including Hirschsprung disease and some cancers Alternative splicing results in multiple transcript variants
Cayman Chemical LDL RECPTR RabbIt MoncLNa 50uL
A phenolic glucoside with in vitro neuroprotective activity reduces glutamate-induced neurotoxicity by 19.3 in PC12 cells at 10 UM
ABclonal Technology WFS1 Rabbit mAb
This gene encodes a transmembrane protein which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain pancreas heart and insulinoma beta-cell lines Mutations in this gene are associated with Wolfram syndrome also called DIDMOAD (Diabetes Insipidus Diabetes Mellitus Optic Atrophy and Deafness) an autosomal recessive disorder The disease affects the brain and central nervous system Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6) also known as DFNA14 or DFNA38 Alternatively spliced transcript variants have been found for this gene